Propionibacterium acnes Induces Intervertebral Disc Degeneration by Promoting iNOS/NO and COX-2/PGE(2) Activation via the ROS-Dependent NF-κB Pathway

Accumulating evidence suggests that Propionibacterium acnes (P. acnes) is a novel pathogenic factor promoting intervertebral disc degeneration (IVDD). However, the underlying mechanisms by which P. acnes induces IVDD have been unclear. In this study, we quantified the severity of IVDD, as well as th...

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Detalles Bibliográficos
Autores principales: Lin, Yazhou, Tang, Guoqing, Jiao, Yucheng, Yuan, Ye, Zheng, Yuehuan, Chen, Yong, Xiao, Jiaqi, Li, Changwei, Chen, Zhe, Cao, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120277/
https://www.ncbi.nlm.nih.gov/pubmed/30210652
http://dx.doi.org/10.1155/2018/3692752

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