Toxic Epidermal Necrolysis in a Patient with Autoimmune Limbic Encephalitis with Anti-Glutamate Receptor Antibodies

We report on a 44-year-old woman who was diagnosed with toxic epidermal necrolysis (TEN) during the recovery phase from autoimmune limbic encephalitis with anti-glutamate receptor antibodies. Both, autoimmune limbic encephalitis and TEN are very rare diseases. The co-existence of the two diseases ha...

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Autores principales: Hatano, Keiko, Matsumoto, Hideyuki, Mitsutake, Akihiko, Yoshimura, Junko, Nomura, Aya, Imakado, Sumihisa, Takahashi, Yukitoshi, Hashida, Hideji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120415/
https://www.ncbi.nlm.nih.gov/pubmed/30186144
http://dx.doi.org/10.1159/000491690
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author Hatano, Keiko
Matsumoto, Hideyuki
Mitsutake, Akihiko
Yoshimura, Junko
Nomura, Aya
Imakado, Sumihisa
Takahashi, Yukitoshi
Hashida, Hideji
author_facet Hatano, Keiko
Matsumoto, Hideyuki
Mitsutake, Akihiko
Yoshimura, Junko
Nomura, Aya
Imakado, Sumihisa
Takahashi, Yukitoshi
Hashida, Hideji
author_sort Hatano, Keiko
collection PubMed
description We report on a 44-year-old woman who was diagnosed with toxic epidermal necrolysis (TEN) during the recovery phase from autoimmune limbic encephalitis with anti-glutamate receptor antibodies. Both, autoimmune limbic encephalitis and TEN are very rare diseases. The co-existence of the two diseases has not yet been reported. We speculate that the total of 18 drugs needed for the treatment of encephalitis might have increased the risk of TEN. Similar reports would be required to elucidate the pathophysiology of the co-existence.
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spelling pubmed-61204152018-09-05 Toxic Epidermal Necrolysis in a Patient with Autoimmune Limbic Encephalitis with Anti-Glutamate Receptor Antibodies Hatano, Keiko Matsumoto, Hideyuki Mitsutake, Akihiko Yoshimura, Junko Nomura, Aya Imakado, Sumihisa Takahashi, Yukitoshi Hashida, Hideji Case Rep Neurol Case Report We report on a 44-year-old woman who was diagnosed with toxic epidermal necrolysis (TEN) during the recovery phase from autoimmune limbic encephalitis with anti-glutamate receptor antibodies. Both, autoimmune limbic encephalitis and TEN are very rare diseases. The co-existence of the two diseases has not yet been reported. We speculate that the total of 18 drugs needed for the treatment of encephalitis might have increased the risk of TEN. Similar reports would be required to elucidate the pathophysiology of the co-existence. S. Karger AG 2018-08-03 /pmc/articles/PMC6120415/ /pubmed/30186144 http://dx.doi.org/10.1159/000491690 Text en Copyright © 2018 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Hatano, Keiko
Matsumoto, Hideyuki
Mitsutake, Akihiko
Yoshimura, Junko
Nomura, Aya
Imakado, Sumihisa
Takahashi, Yukitoshi
Hashida, Hideji
Toxic Epidermal Necrolysis in a Patient with Autoimmune Limbic Encephalitis with Anti-Glutamate Receptor Antibodies
title Toxic Epidermal Necrolysis in a Patient with Autoimmune Limbic Encephalitis with Anti-Glutamate Receptor Antibodies
title_full Toxic Epidermal Necrolysis in a Patient with Autoimmune Limbic Encephalitis with Anti-Glutamate Receptor Antibodies
title_fullStr Toxic Epidermal Necrolysis in a Patient with Autoimmune Limbic Encephalitis with Anti-Glutamate Receptor Antibodies
title_full_unstemmed Toxic Epidermal Necrolysis in a Patient with Autoimmune Limbic Encephalitis with Anti-Glutamate Receptor Antibodies
title_short Toxic Epidermal Necrolysis in a Patient with Autoimmune Limbic Encephalitis with Anti-Glutamate Receptor Antibodies
title_sort toxic epidermal necrolysis in a patient with autoimmune limbic encephalitis with anti-glutamate receptor antibodies
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120415/
https://www.ncbi.nlm.nih.gov/pubmed/30186144
http://dx.doi.org/10.1159/000491690
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