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Oxidative stress and phosphatidylserine exposure in red cells from patients with sickle cell anaemia

Phosphatidylserine (PS) exposure increases as red cells age, and is an important signal for the removal of senescent cells from the circulation. PS exposure is elevated in red cells from sickle cell anaemia (SCA) patients and is thought to enhance haemolysis and vaso‐occlusion. Although precise cond...

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Detalles Bibliográficos
Autores principales: Hannemann, Anke, Rees, David C., Brewin, John N., Noe, Andreas, Low, Ben, Gibson, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120535/
https://www.ncbi.nlm.nih.gov/pubmed/29938778
http://dx.doi.org/10.1111/bjh.15441