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Integrating the DNA damage and protein stress responses during cancer development and treatment

During evolution, cells have developed a wide spectrum of stress response modules to ensure homeostasis. The genome and proteome damage response pathways constitute the pillars of this interwoven ‘defensive’ network. Consequently, the deregulation of these pathways correlates with ageing and various...

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Detalles Bibliográficos
Autores principales: Gorgoulis, Vassilis G, Pefani, Dafni‐Eleftheria, Pateras, Ioannis S, Trougakos, Ioannis P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120562/
https://www.ncbi.nlm.nih.gov/pubmed/29756349
http://dx.doi.org/10.1002/path.5097