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Single-cell RNA-seq analysis identifies markers of resistance to targeted BRAF inhibitors in melanoma cell populations
Single-cell RNA-seq's (scRNA-seq) unprecedented cellular resolution at a genome-wide scale enables us to address questions about cellular heterogeneity that are inaccessible using methods that average over bulk tissue extracts. However, scRNA-seq data sets also present additional challenges suc...
Autores principales: | Ho, Yu-Jui, Anaparthy, Naishitha, Molik, David, Mathew, Grinu, Aicher, Toby, Patel, Ami, Hicks, James, Hammell, Molly Gale |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120620/ https://www.ncbi.nlm.nih.gov/pubmed/30061114 http://dx.doi.org/10.1101/gr.234062.117 |
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