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Single-cell RNA-seq analysis identifies markers of resistance to targeted BRAF inhibitors in melanoma cell populations

Single-cell RNA-seq's (scRNA-seq) unprecedented cellular resolution at a genome-wide scale enables us to address questions about cellular heterogeneity that are inaccessible using methods that average over bulk tissue extracts. However, scRNA-seq data sets also present additional challenges suc...

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Detalles Bibliográficos
Autores principales:	Ho, Yu-Jui, Anaparthy, Naishitha, Molik, David, Mathew, Grinu, Aicher, Toby, Patel, Ami, Hicks, James, Hammell, Molly Gale
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2018
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120620/ https://www.ncbi.nlm.nih.gov/pubmed/30061114 http://dx.doi.org/10.1101/gr.234062.117

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