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Natural genetic variation in C. elegans identified genomic loci controlling metabolite levels

Metabolic homeostasis is sustained by complex biological networks that respond to nutrient availability. Genetic and environmental factors may disrupt this equilibrium, leading to metabolic disorders, including obesity and type 2 diabetes. To identify the genetic factors controlling metabolism, we p...

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Detalles Bibliográficos
Autores principales: Gao, Arwen W., Sterken, Mark G., uit de Bos, Jelmi, van Creij, Jelle, Kamble, Rashmi, Snoek, Basten L., Kammenga, Jan E., Houtkooper, Riekelt H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120624/
https://www.ncbi.nlm.nih.gov/pubmed/30108180
http://dx.doi.org/10.1101/gr.232322.117