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Tracing human stem cell lineage during development using DNA methylation

Stem cell maturation is a fundamental, yet poorly understood aspect of human development. We devised a DNA methylation signature deeply reminiscent of embryonic stem cells (a fetal cell origin signature, FCO) to interrogate the evolving character of multiple human tissues. The cell fraction displayi...

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Detalles Bibliográficos
Autores principales:	Salas, Lucas A., Wiencke, John K., Koestler, Devin C., Zhang, Ze, Christensen, Brock C., Kelsey, Karl T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120629/ https://www.ncbi.nlm.nih.gov/pubmed/30072366 http://dx.doi.org/10.1101/gr.233213.117

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