Cargando…
Death of new microRNA genes in Drosophila via gradual loss of fitness advantages
The prevalence of de novo coding genes is controversial due to length and coding constraints. Noncoding genes, especially small ones, are freer to evolve de novo by comparison. The best examples are microRNAs (miRNAs), a large class of regulatory molecules ∼22 nt in length. Here, we study six de nov...
Autores principales: | Lu, Guang-An, Zhao, Yixin, Yang, Hao, Lan, Ao, Shi, Suhua, Liufu, Zhongqi, Huang, Yumei, Tang, Tian, Xu, Jin, Shen, Xu, Wu, Chung-I |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120634/ https://www.ncbi.nlm.nih.gov/pubmed/30049791 http://dx.doi.org/10.1101/gr.233809.117 |
Ejemplares similares
-
On the possibility of death of new genes – evidence from the deletion of de novo microRNAs
por: Lu, Guang-An, et al.
Publicado: (2018) -
A Rapid Evolving microRNA Cluster Rewires Its Target Regulatory Networks in Drosophila
por: Lyu, Yang, et al.
Publicado: (2021) -
Run or Die in the Evolution of New MicroRNAs—Testing the Red Queen Hypothesis on De Novo New Genes
por: Zhao, Yixin, et al.
Publicado: (2020) -
Redundant and incoherent regulations of multiple phenotypes suggest microRNAs’ role in stability control
por: Liufu, Zhongqi, et al.
Publicado: (2017) -
New MicroRNAs in Drosophila—Birth, Death and Cycles of Adaptive Evolution
por: Lyu, Yang, et al.
Publicado: (2014)