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Signaling pathways and steroid receptors modulating estrogen receptor α function in breast cancer
Estrogen receptor α (ER) is the major driver of ∼75% of breast cancers, and multiple ER targeting drugs are routinely used clinically to treat patients with ER(+) breast cancer. However, many patients relapse on these targeted therapies and ultimately develop metastatic and incurable disease, and un...
Autores principales: | Siersbæk, Rasmus, Kumar, Sanjeev, Carroll, Jason S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120708/ https://www.ncbi.nlm.nih.gov/pubmed/30181360 http://dx.doi.org/10.1101/gad.316646.118 |
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