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STAT3 is a master regulator of epithelial identity and KRAS-driven tumorigenesis

A dichotomy exists regarding the role of signal transducer and activator of transcription 3 (STAT3) in cancer. Functional and genetic studies demonstrate either an intrinsic requirement for STAT3 or a suppressive effect on common types of cancer. These contrasting actions of STAT3 imply context depe...

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Detalles Bibliográficos
Autores principales:	D'Amico, Stephen, Shi, Jiaqi, Martin, Benjamin L., Crawford, Howard C., Petrenko, Oleksi, Reich, Nancy C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120712/ https://www.ncbi.nlm.nih.gov/pubmed/30135074 http://dx.doi.org/10.1101/gad.311852.118

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