TCF3 alternative splicing controlled by hnRNP H/F regulates E-cadherin expression and hESC pluripotency

Alternative splicing (AS) plays important roles in embryonic stem cell (ESC) differentiation. In this study, we first identified transcripts that display specific AS patterns in pluripotent human ESCs (hESCs) relative to differentiated cells. One of these encodes T-cell factor 3 (TCF3), a transcript...

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Detalles Bibliográficos
Autores principales: Yamazaki, Takashi, Liu, Lizhi, Lazarev, Denis, Al-Zain, Amr, Fomin, Vitalay, Yeung, Percy Luk, Chambers, Stuart M., Lu, Chi-Wei, Studer, Lorenz, Manley, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120717/
https://www.ncbi.nlm.nih.gov/pubmed/30115631
http://dx.doi.org/10.1101/gad.316984.118

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