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Dynamic turnover of paused Pol II complexes at human promoters

Paused RNA polymerase II (Pol II) that piles up near most human promoters is the target of mechanisms that control entry into productive elongation. Whether paused Pol II is a stable or dynamic target remains unresolved. We report that most 5′ paused Pol II throughout the genome is turned over withi...

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Detalles Bibliográficos
Autores principales:	Erickson, Benjamin, Sheridan, Ryan M., Cortazar, Michael, Bentley, David L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120720/ https://www.ncbi.nlm.nih.gov/pubmed/30150253 http://dx.doi.org/10.1101/gad.316810.118

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