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The aryl hydrocarbon receptor and interferon gamma generate antiviral states via transcriptional repression

The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor whose activation induces the expression of numerous genes, with many effects on cells. However, AhR activation is not known to affect the replication of viruses. We show that AhR activation in macrophages causes a block t...

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Detalles Bibliográficos
Autores principales:	Kueck, Tonya, Cassella, Elena, Holler, Jessica, Kim, Baek, Bieniasz, Paul D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120754/ https://www.ncbi.nlm.nih.gov/pubmed/30132758 http://dx.doi.org/10.7554/eLife.38867

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