A new meroterpenoid functions as an anti-tumor agent in hepatoma cells by downregulating mTOR activation and inhibiting EMT

Liver cancer, also known as primary liver cancer, is cancer that starts in the liver. JNU-144, a new meroterpenoid purified from Lithospermum erythrorhizon, has exhibited promising anticancer activity; however, the molecular mechanisms of action of JNU-144 on malignant cells remain unclear. Our stud...

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Detalles Bibliográficos
Autores principales: Wan, Haoqiang, Li, Jiemei, Zhang, Keda, Zou, Xiaoting, Ge, Lanlan, Zhu, Fuqiang, Zhou, Huirong, Gong, Minna, Wang, Tianwa, Chen, Dongling, Peng, Shusong, Zhou, Boping, Zeng, Xiaobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120861/
https://www.ncbi.nlm.nih.gov/pubmed/30177727
http://dx.doi.org/10.1038/s41598-018-31409-2

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