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Activation of hepatic stem cells compartment during hepatocarcinogenesis in a HBsAg HBV-transgenic mouse model

Chronic infection of Hepatitis B Virus (HBV) is one of the highest risk factors of hepatocellular carcinoma (HCC). The accumulation of HBV surface antigen (HBsAg) into hepatocytes induces inflammation and oxidative stress, impairing their replicative ability and allowing the activation of the hepati...

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Detalles Bibliográficos
Autores principales:	Anfuso, Beatrice, El-Khobar, Korri E., Ie, Susan I., Avellini, Claudio, Radillo, Oriano, Raseni, Alan, Tiribelli, Claudio, Sukowati, Caecilia H. C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120871/ https://www.ncbi.nlm.nih.gov/pubmed/30177788 http://dx.doi.org/10.1038/s41598-018-31406-5

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