The osteopontin-CD44 axis in hepatic cancer stem cells regulates IFN signaling and HCV replication

Osteopontin (OPN) is involved in cell proliferation, migration, inflammation, and tumor progression in various tissues. OPN induces stemness by interacting with CD44, but the functional relevance of OPN-mediated interferon (IFN) signaling and hepatitis C virus (HCV) replication in stem cell populati...

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Detalles Bibliográficos
Autores principales: Shirasaki, Takayoshi, Honda, Masao, Yamashita, Taro, Nio, Kouki, Shimakami, Tetsuro, Shimizu, Ryougo, Nakasyo, Saki, Murai, Kazuhisa, Shirasaki, Natsumi, Okada, Hikari, Sakai, Yoshio, Sato, Tokiharu, Suzuki, Tetsuro, Yoshioka, Katsuji, Kaneko, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120883/
https://www.ncbi.nlm.nih.gov/pubmed/30177680
http://dx.doi.org/10.1038/s41598-018-31421-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120883/
https://www.ncbi.nlm.nih.gov/pubmed/30177680
http://dx.doi.org/10.1038/s41598-018-31421-6

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