CRISPR/Cas9 Immunoengineering of Hoxb8-Immortalized Progenitor Cells for Revealing CCR7-Mediated Dendritic Cell Signaling and Migration Mechanisms in vivo

To present antigens to cognate T cells, dendritic cells (DCs) exploit the chemokine receptor CCR7 to travel from peripheral tissue via afferent lymphatic vessels to directly enter draining lymph nodes through the floor of the subcapsular sinus. Here, we combined unlimited proliferative capacity of c...

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Detalles Bibliográficos
Autores principales: Hammerschmidt, Swantje I., Werth, Kathrin, Rothe, Michael, Galla, Melanie, Permanyer, Marc, Patzer, Gwendolyn E., Bubke, Anja, Frenk, David N., Selich, Anton, Lange, Lucas, Schambach, Axel, Bošnjak, Berislav, Förster, Reinhold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120996/
https://www.ncbi.nlm.nih.gov/pubmed/30210501
http://dx.doi.org/10.3389/fimmu.2018.01949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120996/
https://www.ncbi.nlm.nih.gov/pubmed/30210501
http://dx.doi.org/10.3389/fimmu.2018.01949

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