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DECtp: Calling Differential Gene Expression Between Cancer and Normal Samples by Integrating Tumor Purity Information

Identifying differentially expressed genes (DEGs) between tumor and normal samples is critical for studying tumorigenesis, and has been routinely applied to identify diagnostic, prognostic, and therapeutic biomarkers for many cancers. It is well-known that solid tumor tissue samples obtained from cl...

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Detalles Bibliográficos
Autores principales: Zhang, Weiwei, Long, Haixia, He, Binsheng, Yang, Jialiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121016/
https://www.ncbi.nlm.nih.gov/pubmed/30210526
http://dx.doi.org/10.3389/fgene.2018.00321