Distinct Modulation of Spontaneous and GABA-Evoked Gating by Flurazepam Shapes Cross-Talk Between Agonist-Free and Liganded GABA(A) Receptor Activity

GABA(A) receptors (GABA(A)Rs) play a crucial inhibitory role in the CNS. Benzodiazepines (BDZs) are positive modulators of specific subtypes of GABA(A)Rs, but the underlying mechanism remains obscure. Early studies demonstrated the major impact of BDZs on binding and more recent investigations indic...

Descripción completa

Detalles Bibliográficos
Autores principales: Jatczak-Śliwa, Magdalena, Terejko, Katarzyna, Brodzki, Marek, Michałowski, Michał A., Czyzewska, Marta M., Nowicka, Joanna M., Andrzejczak, Anna, Srinivasan, Rakenduvadhana, Mozrzymas, Jerzy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121034/
https://www.ncbi.nlm.nih.gov/pubmed/30210295
http://dx.doi.org/10.3389/fncel.2018.00237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121034/
https://www.ncbi.nlm.nih.gov/pubmed/30210295
http://dx.doi.org/10.3389/fncel.2018.00237

Ejemplares similares