The Free Radical Scavenger N-Tert-Butyl-α-Phenylnitrone (PBN) Administered to Immature Rats During Status Epilepticus Alters Neurogenesis and Has Variable Effects, Both Beneficial and Detrimental, on Long-Term Outcomes

Status epilepticus (SE), especially in immature animals, is known to produce recurrent spontaneous seizures and behavioral comorbidities later in life. The cause of these adverse long-term outcomes is unknown, but it has been hypothesized that free radicals produced by SE may play a role. We tested...

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Detalles Bibliográficos
Autores principales: Kubová, Hana, Folbergrová, Jaroslava, Rejchrtová, Jana, Tsenov, Grygoriy, Pařízková, Martina, Burchfiel, James, Mikulecká, Anna, Mareš, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121067/
https://www.ncbi.nlm.nih.gov/pubmed/30210297
http://dx.doi.org/10.3389/fncel.2018.00266

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