Discovery and Identification of Pyrazolopyramidine Analogs as Novel Potent Androgen Receptor Antagonists

Androgen receptor (AR), an important target in the current androgen derivation therapy, plays a critical role in the development and progress of prostate cancer (PCa). Nonsteroidal antiandrogens, such as enzalutamide and bicalutamide, are commonly used in clinic to treat PCa. Though they are very ef...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Lingyan, Song, Tianqing, Wang, Xin, Li, Jiazhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121070/
https://www.ncbi.nlm.nih.gov/pubmed/30210333
http://dx.doi.org/10.3389/fphar.2018.00864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121070/
https://www.ncbi.nlm.nih.gov/pubmed/30210333
http://dx.doi.org/10.3389/fphar.2018.00864

Ejemplares similares