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WWOX Tumor Suppressor Gene in Breast Cancer, a Historical Perspective and Future Directions

The WWOX tumor suppressor gene is located at 16q23. 1–23.2, which covers the region of FRA16D—a common fragile sites. Deletions within the WWOX coding sequence are observed in up to 80% of breast cancer cases, which makes it one of the most common genetic alterations in this tumor type. The WWOX gen...

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Detalles Bibliográficos
Autores principales:	Pospiech, Karolina, Płuciennik, Elzbieta, Bednarek, Andrzej K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121138/ https://www.ncbi.nlm.nih.gov/pubmed/30211123 http://dx.doi.org/10.3389/fonc.2018.00345

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