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Assault-related self-blame and its association with PTSD in sexually assaulted women: an MRI inquiry
Sexual assault is a frequent interpersonal trauma, which often leads to post-traumatic stress disorder (PTSD). Among other postassault characteristics, self-blame attributions were suggested to play an important role in sexually assaulted individuals’ coping and were consistently associated with PTS...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121153/ https://www.ncbi.nlm.nih.gov/pubmed/29939345 http://dx.doi.org/10.1093/scan/nsy044 |
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author | Berman, Zohar Assaf, Yaniv Tarrasch, Ricardo Joel, Daphna |
author_facet | Berman, Zohar Assaf, Yaniv Tarrasch, Ricardo Joel, Daphna |
author_sort | Berman, Zohar |
collection | PubMed |
description | Sexual assault is a frequent interpersonal trauma, which often leads to post-traumatic stress disorder (PTSD). Among other postassault characteristics, self-blame attributions were suggested to play an important role in sexually assaulted individuals’ coping and were consistently associated with PTSD in this population. The present study aimed to elucidate the neural underpinnings that may associate self-blame and PTSD in women who experienced sexual assault at adulthood, using structural and resting-state functional MRI. Thirty-eight sexually assaulted women and 24 non-exposed matched controls were studied (mean age: 25 years). Among the sexually assaulted participants, assault-related self-blame was negatively correlated with gray matter volume (GMV) bilaterally in the lingual gyrus and adjacent intracalcarine cortex. GMV in this cluster was also predicted by intrusion symptoms and negative social reactions. Resting-state functional connectivity (rs-FC) of this cluster with the left anterior temporal fusiform cortex significantly differed between PTSD and non-PTSD sexually assaulted participants, and was inversely correlated with intrusion symptoms and with peritraumatic dissociation. Finally, lingual cluster’s GMV and rs-FC with the anterior fusiform mediated the association between self-blame and intrusion symptoms across sexually assaulted participants. These findings link assault-related self-blame, disrupted postassault recovery and the neural circuitry involved in the processing of traumatic memories. |
format | Online Article Text |
id | pubmed-6121153 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-61211532018-09-06 Assault-related self-blame and its association with PTSD in sexually assaulted women: an MRI inquiry Berman, Zohar Assaf, Yaniv Tarrasch, Ricardo Joel, Daphna Soc Cogn Affect Neurosci Original Article Sexual assault is a frequent interpersonal trauma, which often leads to post-traumatic stress disorder (PTSD). Among other postassault characteristics, self-blame attributions were suggested to play an important role in sexually assaulted individuals’ coping and were consistently associated with PTSD in this population. The present study aimed to elucidate the neural underpinnings that may associate self-blame and PTSD in women who experienced sexual assault at adulthood, using structural and resting-state functional MRI. Thirty-eight sexually assaulted women and 24 non-exposed matched controls were studied (mean age: 25 years). Among the sexually assaulted participants, assault-related self-blame was negatively correlated with gray matter volume (GMV) bilaterally in the lingual gyrus and adjacent intracalcarine cortex. GMV in this cluster was also predicted by intrusion symptoms and negative social reactions. Resting-state functional connectivity (rs-FC) of this cluster with the left anterior temporal fusiform cortex significantly differed between PTSD and non-PTSD sexually assaulted participants, and was inversely correlated with intrusion symptoms and with peritraumatic dissociation. Finally, lingual cluster’s GMV and rs-FC with the anterior fusiform mediated the association between self-blame and intrusion symptoms across sexually assaulted participants. These findings link assault-related self-blame, disrupted postassault recovery and the neural circuitry involved in the processing of traumatic memories. Oxford University Press 2018-06-25 /pmc/articles/PMC6121153/ /pubmed/29939345 http://dx.doi.org/10.1093/scan/nsy044 Text en © The Author(s) (2018). Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Original Article Berman, Zohar Assaf, Yaniv Tarrasch, Ricardo Joel, Daphna Assault-related self-blame and its association with PTSD in sexually assaulted women: an MRI inquiry |
title | Assault-related self-blame and its association with PTSD in sexually assaulted women: an MRI inquiry |
title_full | Assault-related self-blame and its association with PTSD in sexually assaulted women: an MRI inquiry |
title_fullStr | Assault-related self-blame and its association with PTSD in sexually assaulted women: an MRI inquiry |
title_full_unstemmed | Assault-related self-blame and its association with PTSD in sexually assaulted women: an MRI inquiry |
title_short | Assault-related self-blame and its association with PTSD in sexually assaulted women: an MRI inquiry |
title_sort | assault-related self-blame and its association with ptsd in sexually assaulted women: an mri inquiry |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121153/ https://www.ncbi.nlm.nih.gov/pubmed/29939345 http://dx.doi.org/10.1093/scan/nsy044 |
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