Non-canonical role of cancer-associated mutant SEC23B in the ribosome biogenesis pathway

SEC23B is a component of coat protein complex II (COPII) vesicles that transport secretory proteins from the endoplasmic reticulum (ER) to the Golgi apparatus. Loss-of-function SEC23B mutations cause a rare form of anemia, resulting from decreased SEC23B levels. We recently identified germline heter...

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Detalles Bibliográficos
Autores principales: Yehia, Lamis, Jindal, Supriya, Komar, Anton A, Eng, Charis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121187/
https://www.ncbi.nlm.nih.gov/pubmed/29893852
http://dx.doi.org/10.1093/hmg/ddy226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121187/
https://www.ncbi.nlm.nih.gov/pubmed/29893852
http://dx.doi.org/10.1093/hmg/ddy226

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