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High Prevalence of Late-Stage Disease in Newly Diagnosed Human Immunodeficiency Virus Patients in Sierra Leone
A high prevalence of late-stage disease (75.4%) and severe immunosuppression (23.3%) was observed in 155 newly diagnosed human immunodeficiency virus patients in Freetown, Sierra Leone during August to November 2017. Within the late-stage diagnosis group, a significantly high proportion of patients...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121223/ https://www.ncbi.nlm.nih.gov/pubmed/30191158 http://dx.doi.org/10.1093/ofid/ofy208 |
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author | Yendewa, George A Poveda, Eva Lakoh, Sulaiman Yendewa, Sahr A Jiba, Darlinda F Salgado-Barreira, Angel Sahr, Foday Salata, Robert A |
author_facet | Yendewa, George A Poveda, Eva Lakoh, Sulaiman Yendewa, Sahr A Jiba, Darlinda F Salgado-Barreira, Angel Sahr, Foday Salata, Robert A |
author_sort | Yendewa, George A |
collection | PubMed |
description | A high prevalence of late-stage disease (75.4%) and severe immunosuppression (23.3%) was observed in 155 newly diagnosed human immunodeficiency virus patients in Freetown, Sierra Leone during August to November 2017. Within the late-stage diagnosis group, a significantly high proportion of patients reported fever (84.2% vs 65.2%; P = .01), weight loss (82.2% vs 63.5%; P = .01), and malaise (89.7% vs 71.7%; P = .05). Fever was identified as the only independent predictor of late-stage disease in this study. |
format | Online Article Text |
id | pubmed-6121223 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-61212232018-09-06 High Prevalence of Late-Stage Disease in Newly Diagnosed Human Immunodeficiency Virus Patients in Sierra Leone Yendewa, George A Poveda, Eva Lakoh, Sulaiman Yendewa, Sahr A Jiba, Darlinda F Salgado-Barreira, Angel Sahr, Foday Salata, Robert A Open Forum Infect Dis Brief Report A high prevalence of late-stage disease (75.4%) and severe immunosuppression (23.3%) was observed in 155 newly diagnosed human immunodeficiency virus patients in Freetown, Sierra Leone during August to November 2017. Within the late-stage diagnosis group, a significantly high proportion of patients reported fever (84.2% vs 65.2%; P = .01), weight loss (82.2% vs 63.5%; P = .01), and malaise (89.7% vs 71.7%; P = .05). Fever was identified as the only independent predictor of late-stage disease in this study. Oxford University Press 2018-08-23 /pmc/articles/PMC6121223/ /pubmed/30191158 http://dx.doi.org/10.1093/ofid/ofy208 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Brief Report Yendewa, George A Poveda, Eva Lakoh, Sulaiman Yendewa, Sahr A Jiba, Darlinda F Salgado-Barreira, Angel Sahr, Foday Salata, Robert A High Prevalence of Late-Stage Disease in Newly Diagnosed Human Immunodeficiency Virus Patients in Sierra Leone |
title | High Prevalence of Late-Stage Disease in Newly Diagnosed Human Immunodeficiency Virus Patients in Sierra Leone |
title_full | High Prevalence of Late-Stage Disease in Newly Diagnosed Human Immunodeficiency Virus Patients in Sierra Leone |
title_fullStr | High Prevalence of Late-Stage Disease in Newly Diagnosed Human Immunodeficiency Virus Patients in Sierra Leone |
title_full_unstemmed | High Prevalence of Late-Stage Disease in Newly Diagnosed Human Immunodeficiency Virus Patients in Sierra Leone |
title_short | High Prevalence of Late-Stage Disease in Newly Diagnosed Human Immunodeficiency Virus Patients in Sierra Leone |
title_sort | high prevalence of late-stage disease in newly diagnosed human immunodeficiency virus patients in sierra leone |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121223/ https://www.ncbi.nlm.nih.gov/pubmed/30191158 http://dx.doi.org/10.1093/ofid/ofy208 |
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