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Responses of Transgenic Melatonin-Enriched Goats on LPS Stimulation and the Proteogenomic Profiles of Their PBMCs

The anti-inflammatory activity of melatonin (MT) has been well documented; however, little is known regarding endogenously occurring MT in this respect, especially for large animals. In the current study, we created a MT-enriched animal model (goats) overexpressing the MT synthetase gene Aanat. The...

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Detalles Bibliográficos
Autores principales: Yang, Minghui, Tao, Jingli, Wu, Hao, Zhang, Lu, Yao, Yujun, Liu, Lixi, Zhu, Tianqi, Fan, Hao, Cui, Xudai, Dou, Haoran, Liu, Guoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121286/
https://www.ncbi.nlm.nih.gov/pubmed/30111707
http://dx.doi.org/10.3390/ijms19082406