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Inhibition of BET Proteins Reduces Right Ventricle Hypertrophy and Pulmonary Hypertension Resulting from Combined Hypoxia and Pulmonary Inflammation
Pulmonary hypertension is a co-morbidity, which strongly participates in morbi-mortality in patients with chronic obstructive pulmonary disease (COPD). Recent findings showed that bromodomain-containing proteins, in charge of reading histone acetylation, could be involved in pulmonary arterial hyper...
Autores principales: | Chabert, Clovis, Khochbin, Saadi, Rousseaux, Sophie, Veyrenc, Sylvie, Furze, Rebecca, Smithers, Nicholas, Prinjha, Rab K, Schlattner, Uwe, Pison, Christophe, Dubouchaud, Hervé |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121304/ https://www.ncbi.nlm.nih.gov/pubmed/30061518 http://dx.doi.org/10.3390/ijms19082224 |
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