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Innovative Approach of Non-Thermal Plasma Application for Improving the Growth Rate in Chickens
As an innovative technology in biological applications—non-thermal plasma technique—has recently been applied to living cells and tissues. However, it is unclear whether non-thermal plasma treatment can directly regulate the growth and development of livestock. In this study, we exposed four-day-inc...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121326/ https://www.ncbi.nlm.nih.gov/pubmed/30082605 http://dx.doi.org/10.3390/ijms19082301 |
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author | Zhang, Jiao Jiao Wang, Xian Zhong Kwon, Taeho Huynh, Do Luong Chandimali, Nisansala Kim, Nameun Kang, Tae Yoon Ghosh, Mrinmoy Gera, Meeta Lee, Sang Baek Lee, Sung Jin Lee, Wang Shik Kim, Seong Bong Mok, Young Sun Jeong, Dong Kee |
author_facet | Zhang, Jiao Jiao Wang, Xian Zhong Kwon, Taeho Huynh, Do Luong Chandimali, Nisansala Kim, Nameun Kang, Tae Yoon Ghosh, Mrinmoy Gera, Meeta Lee, Sang Baek Lee, Sung Jin Lee, Wang Shik Kim, Seong Bong Mok, Young Sun Jeong, Dong Kee |
author_sort | Zhang, Jiao Jiao |
collection | PubMed |
description | As an innovative technology in biological applications—non-thermal plasma technique—has recently been applied to living cells and tissues. However, it is unclear whether non-thermal plasma treatment can directly regulate the growth and development of livestock. In this study, we exposed four-day-incubated fertilized eggs to plasma at 11.7 kV for 2 min, which was found to be the optimal condition in respect of highest growth rate in chickens. Interestingly, plasma-treated male chickens conspicuously grew faster than females. Plasma treatment regulated the reactive oxygen species homeostasis by controlling the mitochondrial respiratory complex activity and up-regulating the antioxidant defense system. At the same time, growth metabolism was improved due to the increase of growth hormone and insulin-like growth factor 1 and their receptors expression, and the rise of thyroid hormones and adenosine triphosphate levels through the regulation of demethylation levels of growth and hormone biosynthesis-related genes in the skeletal muscles and thyroid glands. To our knowledge, this study was the first to evaluate the effects of a non-thermal plasma treatment on the growth rate of chickens. This safe strategy might be beneficial to the livestock industry. |
format | Online Article Text |
id | pubmed-6121326 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61213262018-09-07 Innovative Approach of Non-Thermal Plasma Application for Improving the Growth Rate in Chickens Zhang, Jiao Jiao Wang, Xian Zhong Kwon, Taeho Huynh, Do Luong Chandimali, Nisansala Kim, Nameun Kang, Tae Yoon Ghosh, Mrinmoy Gera, Meeta Lee, Sang Baek Lee, Sung Jin Lee, Wang Shik Kim, Seong Bong Mok, Young Sun Jeong, Dong Kee Int J Mol Sci Article As an innovative technology in biological applications—non-thermal plasma technique—has recently been applied to living cells and tissues. However, it is unclear whether non-thermal plasma treatment can directly regulate the growth and development of livestock. In this study, we exposed four-day-incubated fertilized eggs to plasma at 11.7 kV for 2 min, which was found to be the optimal condition in respect of highest growth rate in chickens. Interestingly, plasma-treated male chickens conspicuously grew faster than females. Plasma treatment regulated the reactive oxygen species homeostasis by controlling the mitochondrial respiratory complex activity and up-regulating the antioxidant defense system. At the same time, growth metabolism was improved due to the increase of growth hormone and insulin-like growth factor 1 and their receptors expression, and the rise of thyroid hormones and adenosine triphosphate levels through the regulation of demethylation levels of growth and hormone biosynthesis-related genes in the skeletal muscles and thyroid glands. To our knowledge, this study was the first to evaluate the effects of a non-thermal plasma treatment on the growth rate of chickens. This safe strategy might be beneficial to the livestock industry. MDPI 2018-08-06 /pmc/articles/PMC6121326/ /pubmed/30082605 http://dx.doi.org/10.3390/ijms19082301 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zhang, Jiao Jiao Wang, Xian Zhong Kwon, Taeho Huynh, Do Luong Chandimali, Nisansala Kim, Nameun Kang, Tae Yoon Ghosh, Mrinmoy Gera, Meeta Lee, Sang Baek Lee, Sung Jin Lee, Wang Shik Kim, Seong Bong Mok, Young Sun Jeong, Dong Kee Innovative Approach of Non-Thermal Plasma Application for Improving the Growth Rate in Chickens |
title | Innovative Approach of Non-Thermal Plasma Application for Improving the Growth Rate in Chickens |
title_full | Innovative Approach of Non-Thermal Plasma Application for Improving the Growth Rate in Chickens |
title_fullStr | Innovative Approach of Non-Thermal Plasma Application for Improving the Growth Rate in Chickens |
title_full_unstemmed | Innovative Approach of Non-Thermal Plasma Application for Improving the Growth Rate in Chickens |
title_short | Innovative Approach of Non-Thermal Plasma Application for Improving the Growth Rate in Chickens |
title_sort | innovative approach of non-thermal plasma application for improving the growth rate in chickens |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121326/ https://www.ncbi.nlm.nih.gov/pubmed/30082605 http://dx.doi.org/10.3390/ijms19082301 |
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