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IL-37 Expression Reduces Lean Body Mass in Mice by Reducing Food Intake

The human cytokine interleukin (IL)-37 is an anti-inflammatory member of the IL-1 family of cytokines. Transgenic expression of IL-37 in mice protects them from diet-induced obesity and associated metabolic complications including dyslipidemia, inflammation and insulin resistance. The precise mechan...

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Detalles Bibliográficos
Autores principales: Kuipers, Eline N., van Dam, Andrea D., Ballak, Dov B., de Wit, Ellemiek A., Dinarello, Charles A., Stienstra, Rinke, van Diepen, Janna A., Rensen, Patrick C.N., Boon, Mariëtte R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121375/
https://www.ncbi.nlm.nih.gov/pubmed/30072596
http://dx.doi.org/10.3390/ijms19082264