Trans-Ferulic Acid-4-β-Glucoside Alleviates Cold-Induced Oxidative Stress and Promotes Cold Tolerance

Trans-ferulic acid-4-β-glucoside (C(16)H(20)O(9), TFA-4β-G) is a monomer extracted from the Chinese medicine called radix aconiti carmichaeli (Fuzi). To date, research on this substance is lacking. Here, we found that trans-ferulic acid-4-β-glucoside effectively promoted cold acclimatization in mice...

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Detalles Bibliográficos
Autores principales: Xue, Chong, Lu, Huanyu, Liu, Ying, Zhang, Jianbin, Wang, Jiye, Luo, Wenjing, Zhang, Wenbin, Chen, Jingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121433/
https://www.ncbi.nlm.nih.gov/pubmed/30096768
http://dx.doi.org/10.3390/ijms19082321
Descripción
Sumario:Trans-ferulic acid-4-β-glucoside (C(16)H(20)O(9), TFA-4β-G) is a monomer extracted from the Chinese medicine called radix aconiti carmichaeli (Fuzi). To date, research on this substance is lacking. Here, we found that trans-ferulic acid-4-β-glucoside effectively promoted cold acclimatization in mice via increased heat production and alleviation of oxidative stress in a cold environment. Thus, our work indicates that ferulic acid-4-β-glucoside is a potential therapeutic candidate for prevention and treatment of cold stress injury.

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