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NOX Inhibition Improves β-Adrenergic Stimulated Contractility and Intracellular Calcium Handling in the Aged Rat Heart
Cardiac aging is characterized by alterations in contractility and intracellular calcium ([Ca(2+)](i)) homeostasis. It has been suggested that oxidative stress may be involved in this process. We and others have reported that in cardiomyopathies the NADPH oxidase (NOX)-derived superoxide is increase...
Autores principales: | Valdés, Álvaro, Treuer, Adriana V., Barrios, Guillermo, Ponce, Nikol, Fuentealba, Roberto, Dulce, Raul A., González, Daniel R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121436/ https://www.ncbi.nlm.nih.gov/pubmed/30111689 http://dx.doi.org/10.3390/ijms19082404 |
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