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Contribution of STAT3 to Inflammatory and Fibrotic Diseases and Prospects for its Targeting for Treatment
Signal transducer and activator of transcription (STAT) 3 plays a central role in the host response to injury. It is activated rapidly within cells by many cytokines, most notably those in the IL-6 family, leading to pro-proliferative and pro-survival programs that assist the host in regaining homeo...
Autores principales: | Kasembeli, Moses M., Bharadwaj, Uddalak, Robinson, Prema, Tweardy, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121470/ https://www.ncbi.nlm.nih.gov/pubmed/30081609 http://dx.doi.org/10.3390/ijms19082299 |
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