Phytochemicals in Helicobacter pylori Infections: What Are We Doing Now?

In this critical review, plant sources used as effective antibacterial agents against Helicobacter pylori infections are carefully described. The main intrinsic bioactive molecules, responsible for the observed effects are also underlined and their corresponding modes of action specifically highligh...

Descripción completa

Detalles Bibliográficos
Autores principales: Salehi, Bahare, Sharopov, Farukh, Martorell, Miquel, Rajkovic, Jovana, Ademiluyi, Adedayo Oluwaseun, Sharifi-Rad, Mehdi, Fokou, Patrick Valere Tsouh, Martins, Natália, Iriti, Marcello, Sharifi-Rad, Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121492/
https://www.ncbi.nlm.nih.gov/pubmed/30103451
http://dx.doi.org/10.3390/ijms19082361
_version_ 1783352480734642176
author Salehi, Bahare
Sharopov, Farukh
Martorell, Miquel
Rajkovic, Jovana
Ademiluyi, Adedayo Oluwaseun
Sharifi-Rad, Mehdi
Fokou, Patrick Valere Tsouh
Martins, Natália
Iriti, Marcello
Sharifi-Rad, Javad
author_facet Salehi, Bahare
Sharopov, Farukh
Martorell, Miquel
Rajkovic, Jovana
Ademiluyi, Adedayo Oluwaseun
Sharifi-Rad, Mehdi
Fokou, Patrick Valere Tsouh
Martins, Natália
Iriti, Marcello
Sharifi-Rad, Javad
author_sort Salehi, Bahare
collection PubMed
description In this critical review, plant sources used as effective antibacterial agents against Helicobacter pylori infections are carefully described. The main intrinsic bioactive molecules, responsible for the observed effects are also underlined and their corresponding modes of action specifically highlighted. In addition to traditional uses as herbal remedies, in vitro and in vivo studies focusing on plant extracts and isolated bioactive compounds with anti-H. pylori activity are also critically discussed. Lastly, special attention was also given to plant extracts with urease inhibitory effects, with emphasis on involved modes of action.
format Online
Article
Text
id pubmed-6121492
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-61214922018-09-07 Phytochemicals in Helicobacter pylori Infections: What Are We Doing Now? Salehi, Bahare Sharopov, Farukh Martorell, Miquel Rajkovic, Jovana Ademiluyi, Adedayo Oluwaseun Sharifi-Rad, Mehdi Fokou, Patrick Valere Tsouh Martins, Natália Iriti, Marcello Sharifi-Rad, Javad Int J Mol Sci Review In this critical review, plant sources used as effective antibacterial agents against Helicobacter pylori infections are carefully described. The main intrinsic bioactive molecules, responsible for the observed effects are also underlined and their corresponding modes of action specifically highlighted. In addition to traditional uses as herbal remedies, in vitro and in vivo studies focusing on plant extracts and isolated bioactive compounds with anti-H. pylori activity are also critically discussed. Lastly, special attention was also given to plant extracts with urease inhibitory effects, with emphasis on involved modes of action. MDPI 2018-08-10 /pmc/articles/PMC6121492/ /pubmed/30103451 http://dx.doi.org/10.3390/ijms19082361 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Salehi, Bahare
Sharopov, Farukh
Martorell, Miquel
Rajkovic, Jovana
Ademiluyi, Adedayo Oluwaseun
Sharifi-Rad, Mehdi
Fokou, Patrick Valere Tsouh
Martins, Natália
Iriti, Marcello
Sharifi-Rad, Javad
Phytochemicals in Helicobacter pylori Infections: What Are We Doing Now?
title Phytochemicals in Helicobacter pylori Infections: What Are We Doing Now?
title_full Phytochemicals in Helicobacter pylori Infections: What Are We Doing Now?
title_fullStr Phytochemicals in Helicobacter pylori Infections: What Are We Doing Now?
title_full_unstemmed Phytochemicals in Helicobacter pylori Infections: What Are We Doing Now?
title_short Phytochemicals in Helicobacter pylori Infections: What Are We Doing Now?
title_sort phytochemicals in helicobacter pylori infections: what are we doing now?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121492/
https://www.ncbi.nlm.nih.gov/pubmed/30103451
http://dx.doi.org/10.3390/ijms19082361
work_keys_str_mv AT salehibahare phytochemicalsinhelicobacterpyloriinfectionswhatarewedoingnow
AT sharopovfarukh phytochemicalsinhelicobacterpyloriinfectionswhatarewedoingnow
AT martorellmiquel phytochemicalsinhelicobacterpyloriinfectionswhatarewedoingnow
AT rajkovicjovana phytochemicalsinhelicobacterpyloriinfectionswhatarewedoingnow
AT ademiluyiadedayooluwaseun phytochemicalsinhelicobacterpyloriinfectionswhatarewedoingnow
AT sharifiradmehdi phytochemicalsinhelicobacterpyloriinfectionswhatarewedoingnow
AT fokoupatrickvaleretsouh phytochemicalsinhelicobacterpyloriinfectionswhatarewedoingnow
AT martinsnatalia phytochemicalsinhelicobacterpyloriinfectionswhatarewedoingnow
AT iritimarcello phytochemicalsinhelicobacterpyloriinfectionswhatarewedoingnow
AT sharifiradjavad phytochemicalsinhelicobacterpyloriinfectionswhatarewedoingnow

Ejemplares similares