Synthesis, Biological Evaluation and Molecular Docking of Novel Indole-Aminoquinazoline Hybrids for Anticancer Properties

A series of indole-aminoquinazolines was prepared via amination of the 2-aryl-4-chloroquinazolines with the 7-amino-2-aryl-5-bromoindoles. It was then evaluated for cytotoxicity in vitro against human lung cancer (A549), epithelial colorectal adenocarcinoma (Caco-2), hepatocellular carcinoma (C3A),...

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Detalles Bibliográficos
Autores principales: Mphahlele, Malose J., Mmonwa, Mmakwena M., Aro, Abimbola, McGaw, Lyndy J., Choong, Yee Siew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121530/
https://www.ncbi.nlm.nih.gov/pubmed/30065164
http://dx.doi.org/10.3390/ijms19082232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121530/
https://www.ncbi.nlm.nih.gov/pubmed/30065164
http://dx.doi.org/10.3390/ijms19082232

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