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Real-Time Imaging Reveals Augmentation of Glutamate-Induced Ca(2+) Transients by the NO-cGMP Pathway in Cerebellar Granule Neurons

Dysfunctions of NO-cGMP signaling have been implicated in various neurological disorders. We have studied the potential crosstalk of cGMP and Ca(2+) signaling in cerebellar granule neurons (CGNs) by simultaneous real-time imaging of these second messengers in living cells. The NO donor DEA/NO evoked...

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Detalles Bibliográficos
Autores principales: Paolillo, Michael, Peters, Stefanie, Schramm, Andrea, Schlossmann, Jens, Feil, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121606/
https://www.ncbi.nlm.nih.gov/pubmed/30049956
http://dx.doi.org/10.3390/ijms19082185