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The Protein Phosphatase PPM1G Destabilizes HIF-1α Expression
Hypoxia-inducible factors (HIFs) are key regulators of hypoxic responses, and their stability and transcriptional activity are controlled by several kinases. However, the regulation of HIF by protein phosphatases has not been thoroughly investigated. Here, we found that overexpression of Mg(2+)/Mn(2...
Autores principales: | Pyo, Jaehyuk, Ryu, Jaewook, Kim, Wootae, Choi, Jae-Sun, Jeong, Joo-Won, Kim, Ja-Eun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121667/ https://www.ncbi.nlm.nih.gov/pubmed/30081604 http://dx.doi.org/10.3390/ijms19082297 |
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