Pan-Cancer Analysis Reveals Differential Susceptibility of Bidirectional Gene Promoters to DNA Methylation, Somatic Mutations, and Copy Number Alterations

Bidirectional gene promoters affect the transcription of two genes, leading to the hypothesis that they should exhibit protection against genetic or epigenetic changes in cancer. Therefore, they provide an excellent opportunity to learn about promoter susceptibility to somatic alteration in tumors....

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Detalles Bibliográficos
Autores principales: Thompson, Jeffrey A., Christensen, Brock C., Marsit, Carmen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121907/
https://www.ncbi.nlm.nih.gov/pubmed/30081598
http://dx.doi.org/10.3390/ijms19082296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121907/
https://www.ncbi.nlm.nih.gov/pubmed/30081598
http://dx.doi.org/10.3390/ijms19082296

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