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Fatty liver disrupts glycerol metabolism in gluconeogenic and lipogenic pathways in humans

It is a challenge to assess metabolic dysregulation in fatty liver of human patients prior to clinical manifestations. Here, we recruited obese, but otherwise healthy, subjects to examine biochemical processes in the liver with simple triglyceride accumulation using stable isotopes and NMR analysis...

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Detalles Bibliográficos
Autores principales: Jin, Eunsook S., Browning, Jeffrey D., Murphy, Rebecca E., Malloy, Craig R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121920/
https://www.ncbi.nlm.nih.gov/pubmed/30054343
http://dx.doi.org/10.1194/jlr.M086405