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Single-Strand Break End Resection in Genome Integrity: Mechanism and Regulation by APE2

DNA single-strand breaks (SSBs) occur more than 10,000 times per mammalian cell each day, representing the most common type of DNA damage. Unrepaired SSBs compromise DNA replication and transcription programs, leading to genome instability. Unrepaired SSBs are associated with diseases such as cancer...

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Detalles Bibliográficos
Autores principales:	Hossain, Md. Akram, Lin, Yunfeng, Yan, Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122073/ https://www.ncbi.nlm.nih.gov/pubmed/30110897 http://dx.doi.org/10.3390/ijms19082389

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