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Identification of key pathways and biomarkers in sorafenib-resistant hepatocellular carcinoma using bioinformatics analysis

Hepatocellular carcinoma (HCC) is one of the most common malignant types of cancer, with a high mortality rate. Sorafenib is the sole approved oral clinical therapy against advanced HCC. However, individual patients exhibit varying responses to sorafenib and the development of sorafenib resistance h...

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Detalles Bibliográficos
Autores principales: Huang, Danping, Yuan, Weiqu, Li, Hanmin, Li, Shaodong, Chen, Zuanguang, Yang, Hongzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122189/
https://www.ncbi.nlm.nih.gov/pubmed/30186410
http://dx.doi.org/10.3892/etm.2018.6427