Activation of the Nuclear Erythroid 2-Related Factor 2 Antioxidant Responsive Element (Nrf2-ARE) Signaling Pathway Alleviates Acute Graft-Versus-Host Disease by Reducing Oxidative Stress and Inhibiting Infiltration of Inflammatory Cells in an Allogeneic Stem Cell Transplantation Mouse Model

BACKGROUND: Acute graft-versus-host disease (aGVHD) limits the wider application of hematopoietic stem cell transplantation (HSCT). We explored the relationship between the Nrf2-ARE signaling pathway and aGVHD and identified effective and efficient therapeutic targets for the prevention and manageme...

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Detalles Bibliográficos
Autores principales: Yi, Ting, Li, Xiaogang, Wang, Erhua, Zhang, Yanan, Fu, Yunfeng, Li, Jieping, Jiang, Tiebin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122273/
https://www.ncbi.nlm.nih.gov/pubmed/30148822
http://dx.doi.org/10.12659/MSM.908130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122273/
https://www.ncbi.nlm.nih.gov/pubmed/30148822
http://dx.doi.org/10.12659/MSM.908130

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