Cargando…

Activation of the Nuclear Erythroid 2-Related Factor 2 Antioxidant Responsive Element (Nrf2-ARE) Signaling Pathway Alleviates Acute Graft-Versus-Host Disease by Reducing Oxidative Stress and Inhibiting Infiltration of Inflammatory Cells in an Allogeneic Stem Cell Transplantation Mouse Model

BACKGROUND: Acute graft-versus-host disease (aGVHD) limits the wider application of hematopoietic stem cell transplantation (HSCT). We explored the relationship between the Nrf2-ARE signaling pathway and aGVHD and identified effective and efficient therapeutic targets for the prevention and manageme...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yi, Ting, Li, Xiaogang, Wang, Erhua, Zhang, Yanan, Fu, Yunfeng, Li, Jieping, Jiang, Tiebin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2018
Materias:	Animal Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122273/ https://www.ncbi.nlm.nih.gov/pubmed/30148822 http://dx.doi.org/10.12659/MSM.908130

Ejemplares similares

Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Mediates Neuroprotection in Traumatic Brain Injury at Least in Part by Inactivating Microglia
por: Wu, Gang, et al.
Publicado: (2016)

Melatonin Upregulates Nuclear Factor Erythroid-2 Related Factor 2 (Nrf2) and Mediates Mitophagy to Protect Against Early Brain Injury After Subarachnoid Hemorrhage
por: Sun, Bin, et al.
Publicado: (2018)

Alleviation of Acute Lung Injury in Rats with Sepsis by Resveratrol via the Phosphatidylinositol 3-Kinase/Nuclear Factor-Erythroid 2 Related Factor 2/Heme Oxygenase-1 (PI3K/Nrf2/HO-1) Pathway
por: Wang, Yu, et al.
Publicado: (2018)

The Effects of Dimethyl Fumarate on Atherosclerosis in the Apolipoprotein E-Deficient Mouse Model with Streptozotocin-Induced Hyperglycemia Mediated By the Nuclear Factor Erythroid 2-Related Factor 2/Antioxidant Response Element (Nrf2/ARE) Signaling Pathway
por: Luo, Man, et al.
Publicado: (2019)

Scutellarin Prevents Nonalcoholic Fatty Liver Disease (NAFLD) and Hyperlipidemia via PI3K/AKT-Dependent Activation of Nuclear Factor (Erythroid-Derived 2)-Like 2 (Nrf2) in Rats
por: Fan, Hua, et al.
Publicado: (2017)

Post-Treatment Sevoflurane Protects Against Hypoxic-Ischemic Brain Injury in Neonatal Rats by Downregulating Histone Methyltransferase G9a and Upregulating Nuclear Factor Erythroid 2-Related Factor 2 (NRF2)
por: Wang, HuaiMing, et al.
Publicado: (2021)

Protective Effects of Ischemic Postconditioning on Livers in Rats with Limb Ischemia-Reperfusion via Glycogen Synthase Kinase 3 beta (GSK-3β)/Fyn/Nuclear Receptor-Erythroid-2-Related Factor (Nrf2) Pathway
por: Niu, Qibing, et al.
Publicado: (2020)

ZJ01, a Small Molecule Inhibitor of the Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 (Keap1-Nrf2) Protein-Protein Interaction, Reduces Hyperoxic Acute Lung Injury in a Mouse Model
por: Wan, Jun, et al.
Publicado: (2020)

Tetrahydropyrimidines, ZL-5015 Alleviated Lipopolysaccharide (LPS)-Induced Acute Pneumonia in Rats by Activating the NRF-2/HO-1 Pathway
por: Sun, Wei, et al.
Publicado: (2020)

Alisma Shugan Decoction (ASD) Ameliorates Hepatotoxicity and Associated Liver Dysfunction by Inhibiting Oxidative Stress and p65/Nrf2/JunD Signaling Dysregulation In Vivo
por: Sun, Yunfeng, et al.
Publicado: (2020)

Ganoderma Lucidum Polysaccharides Ameliorates Hepatic Steatosis and Oxidative Stress in db/db Mice via Targeting Nuclear Factor E2 (Erythroid-Derived 2)-Related Factor-2/Heme Oxygenase-1 (HO-1) Pathway
por: Li, Hong Ning, et al.
Publicado: (2020)

Lutein Suppresses Oxidative Stress and Inflammation by Nrf2 Activation in an Osteoporosis Rat Model
por: Li, Hongtao, et al.
Publicado: (2018)

L-Carnitine Reduces Myocardial Oxidative Stress and Alleviates Myocardial Ischemia-Reperfusion Injury by Activating Nuclear Transcription-Related Factor 2 (Nrf2)/Heme Oxygenase-1 (HO-1) Signaling Pathway
por: Zhao, Tana, et al.
Publicado: (2020)

The Potential Role of Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) in Glaucoma: A Review
por: Wang, Mingxuan, et al.
Publicado: (2020)

Mesenchymal Stem Cells Decrease M1/M2 Ratio and Alleviate Inflammation to Improve Limb Ischemia in Mice
por: Song, Ye, et al.
Publicado: (2020)

Catalpol Exerts an Anti-Epilepticus Effect, Possibly by Regulating the Nrf2-Keap1-ARE Signaling Pathway
por: Gao, Jing, et al.
Publicado: (2018)

PARP2 poly(ADP-ribosyl)ates nuclear factor erythroid 2-related factor 2 (NRF2) affecting NRF2 subcellular localization
por: Jankó, Laura, et al.
Publicado: (2023)

Effects of β-Asarone on Ischemic Stroke in Middle Cerebral Artery Occlusion Rats by an Nrf2-Antioxidant Response Elements (ARE) Pathway-Dependent Mechanism
por: Pan, Huiying, et al.
Publicado: (2021)

Clinicopathological significance of nuclear factor (erythroid-2)-related factor 2 (Nrf2) expression in gastric cancer
por: Kawasaki, Yota, et al.
Publicado: (2015)

Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2) and Mitochondrial Dynamics/Mitophagy in Neurological Diseases
por: Kang, Tae-Cheon
Publicado: (2020)

Competition of nuclear factor-erythroid 2 factors related transcription factor isoforms, Nrf1 and Nrf2, in antioxidant enzyme induction()
por: Chepelev, Nikolai L., et al.
Publicado: (2013)

Plumbagin Mediates Cardioprotection Against Myocardial Ischemia/Reperfusion Injury Through Nrf-2 Signaling
por: Wang, Shi-Xun, et al.
Publicado: (2016)

Administration of Hydrogen-Rich Saline in Mice with Allogeneic Hematopoietic Stem-Cell Transplantation
por: Yuan, Lijuan, et al.
Publicado: (2015)

Basic Concepts on the Role of Nuclear Factor Erythroid-Derived 2-Like 2 (Nrf2) in Age-Related Diseases
por: Francisqueti-Ferron, Fabiane Valentini, et al.
Publicado: (2019)

Nrf2 in TIME: The Emerging Role of Nuclear Factor Erythroid 2-Related Factor 2 in the Tumor Immune Microenvironment
por: Feng, Jialin, et al.
Publicado: (2023)

Extracellular Vesicles Derived from Adipose Mesenchymal Stem Cells Alleviate PM2.5-Induced Lung Injury and Pulmonary Fibrosis
por: Gao, Yongheng, et al.
Publicado: (2020)

Protective Effects of Astragaloside IV Combined with Budesonide in Bronchitis in Rats by Regulation of Nrf2/Keap1 Pathway
por: Zhang, Zhijie, et al.
Publicado: (2018)

Therapeutic Effect of Sodium Glucose Co-Transporter 2 Inhibitor Dapagliflozin on Renal Cell Carcinoma
por: Kuang, Haoyu, et al.
Publicado: (2017)

Nuclear factor erythroid 2–related factor 2 (Nrf2) deficiency causes age-dependent progression of female osteoporosis
por: Kubo, Yusuke, et al.
Publicado: (2022)

An essential RNA element resides in a central region of hepatitis E virus ORF2
por: Emerson, Suzanne U., et al.
Publicado: (2013)

Acquired factor V inhibitors after allogeneic hematopoietic stem cell transplantation in a dog
por: Masciana, Joseph, et al.
Publicado: (2020)

Selection and T-cell antigenicity of synthetic long peptides derived from SARS-CoV-2
por: Piadel, Katarzyna, et al.
Publicado: (2022)

The Effects of Nuclear Factor Erythroid 2 (NFE2)-Related Factor 2 (Nrf2) Activation in Preclinical Models of Peripheral Neuropathic Pain
por: Basu, Paramita, et al.
Publicado: (2022)

Mesenchymal Stem Cells Alleviate Acute Lung Injury and Inflammatory Responses Induced by Paraquat Poisoning
por: Zhang, Lichun, et al.
Publicado: (2019)

Melatonin alleviates lipopolysaccharide (LPS) / adenosine triphosphate (ATP)-induced pyroptosis in rat alveolar Type II cells (RLE-6TN) through nuclear factor erythroid 2-related factor 2 (Nrf2)-driven reactive oxygen species (ROS) downregulation
por: Zhou, Tao, et al.
Publicado: (2022)

Astragaloside IV alleviates heart failure by modulating Nrf-2
por: Feng, Wenxiao, et al.
Publicado: (2022)

Upstream Distal Regulatory Elements Contact the Lmo2 Promoter in Mouse Erythroid Cells
por: Bhattacharya, Anandi, et al.
Publicado: (2012)

Downregulated Nuclear Factor E2-Related Factor 2 (Nrf2) Aggravates Cognitive Impairments via Neuroinflammation and Synaptic Plasticity in the Senescence-Accelerated Mouse Prone 8 (SAMP8) Mouse: A Model of Accelerated Senescence
por: Ren, Hui Ling, et al.
Publicado: (2018)

Lipopolysaccharide Exposure Alleviates Asthma in Mice by Regulating Th1/Th2 and Treg/Th17 Balance
por: Ding, Fengxia, et al.
Publicado: (2018)

Inhibition of nuclear factor-erythroid 2–related factor (Nrf2) by caveolin-1 promotes stress-induced premature senescence
por: Volonte, Daniela, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_shqcbhd6brebfp4u6kkecjl9i9