Cargando…

Baicalin and puerarin reverse epithelial-mesenchymal transition via the TGF-β1/Smad3 pathway in vitro

Epithelial-mesenchymal transition (EMT) occurs in the development of fibrosis and carcinogenesis. EMT is associated with chronic liver injury. Evidence shows that hepatocytes undergo EMT in the adult liver. The Qinggan Huoxue Recipe (QGHXR), a Traditional Chinese Medicinal formula, shows a range of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Tao, Liu, Tao, Xing, Lianjun, Ji, Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122322/ https://www.ncbi.nlm.nih.gov/pubmed/30186426 http://dx.doi.org/10.3892/etm.2018.6400

Ejemplares similares

Baicalin inhibits the TGF-β1/p-Smad3 pathway to suppress epithelial-mesenchymal transition-induced metastasis in breast cancer
por: Liu, Ding-Kuo, et al.
Publicado: (2020)

Puerarin Protects against Cardiac Fibrosis Associated with the Inhibition of TGF-β1/Smad2-Mediated Endothelial-to-Mesenchymal Transition
por: Jin, Ya-Ge, et al.
Publicado: (2017)

Isoliquiritigenin Reverses Epithelial-Mesenchymal Transition Through Modulation of the TGF-β/Smad Signaling Pathway in Endometrial Cancer
por: Chen, Hsin-Yuan, et al.
Publicado: (2021)

SUMOylation of Smad2 mediates TGF-β-regulated endothelial–mesenchymal transition
por: Su, Qi, et al.
Publicado: (2023)

Loss of N-Myc interactor promotes epithelial-mesenchymal-transition by activation of TGF-β/SMAD signaling
por: Devine, Daniel J., et al.
Publicado: (2013)

Suppression of Hepatic Epithelial-to-Mesenchymal Transition by Melittin via Blocking of TGFβ/Smad and MAPK-JNK Signaling Pathways
por: Park, Ji-Hyun, et al.
Publicado: (2017)

RUNX3 inhibits the invasion and migration of esophageal squamous cell carcinoma by reversing the epithelial-mesenchymal transition through TGF-β/Smad signaling
por: Xiao, Zhaohua, et al.
Publicado: (2020)

Thalidomide Inhibits TGF-β1-induced Epithelial to Mesenchymal Transition in Alveolar Epithelial Cells via Smad-Dependent and Smad-Independent Signaling Pathways
por: Zhou, Xian-Long, et al.
Publicado: (2017)

CDCA7 promotes TGF‐β‐induced epithelial–mesenchymal transition via transcriptionally regulating Smad4/Smad7 in ESCC
por: Li, Hongyi, et al.
Publicado: (2022)

Role of glycosylation in TGF-β signaling and epithelial-to-mesenchymal transition in cancer
por: Zhang, Jing, et al.
Publicado: (2020)

Baicalin protects against renal interstitial fibrosis in mice by inhibiting the TGF-β/Smad signalling pathway
por: Wang, Hui, et al.
Publicado: (2022)

Suppression of AGR2 in a TGF-β-induced Smad regulatory pathway mediates epithelial-mesenchymal transition
por: Sommerova, Lucia, et al.
Publicado: (2017)

Possible involvement of TGF-β-SMAD-mediated epithelial-mesenchymal transition in pro-metastatic property of PAX6
por: Jin, Meng, et al.
Publicado: (2020)

Reversible Human TGF-β Signal Shifting between Tumor Suppression and Fibro-Carcinogenesis: Implications of Smad Phospho-Isoforms for Hepatic Epithelial-Mesenchymal Transitions
por: Yoshida, Katsunori, et al.
Publicado: (2016)

Isoviolanthin Extracted from Dendrobium officinale Reverses TGF-β1-Mediated Epithelial–Mesenchymal Transition in Hepatocellular Carcinoma Cells via Deactivating the TGF-β/Smad and PI3K/Akt/mTOR Signaling Pathways
por: Xing, Shangping, et al.
Publicado: (2018)

Sinomenine Relieves Airway Remodeling By Inhibiting Epithelial-Mesenchymal Transition Through Downregulating TGF-β1 and Smad3 Expression In Vitro and In Vivo
por: He, Hongjuan, et al.
Publicado: (2021)

ShcA Protects against Epithelial–Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation
por: Muthusamy, Baby Periyanayaki, et al.
Publicado: (2015)

TGF-β/SMAD4-Regulated LncRNA-LINP1 Inhibits Epithelial-Mesenchymal Transition in Lung Cancer
por: Zhang, Chong, et al.
Publicado: (2018)

Repression of Smad4 by MicroRNA-1285 moderates TGF-β-induced epithelial–mesenchymal transition in proliferative vitreoretinopathy
por: Pao, Shu-I, et al.
Publicado: (2021)

LASP1 Induces Epithelial-Mesenchymal Transition in Lung Cancer through the TGF-β1/Smad/Snail Pathway
por: Xue, Qingming, et al.
Publicado: (2021)

Catalpol Attenuates Pulmonary Fibrosis by Inhibiting Ang II/AT(1) and TGF-β/Smad-Mediated Epithelial Mesenchymal Transition
por: Yu, Qun, et al.
Publicado: (2022)

GOLM1 Promotes Epithelial-Mesenchymal Transition by Activating TGFβ1/Smad2 Signaling in Prostate Cancer
por: Qin, Xuke, et al.
Publicado: (2023)

Mechanisms of TGFβ-Induced Epithelial–Mesenchymal Transition
por: Moustakas, Aristidis, et al.
Publicado: (2016)

Overexpression of BMP-7 reverses TGF-β1-induced epithelial-mesenchymal transition by attenuating the Wnt3/β-catenin and TGF-β1/Smad2/3 signaling pathways in HK-2 cells
por: Song, Yan, et al.
Publicado: (2020)

MicroRNA-133b targets TGFβ receptor I to inhibit TGF-β-induced epithelial-to-mesenchymal transition and metastasis by suppressing the TGF-β/SMAD pathway in breast cancer
por: WANG, SHENGJIE, et al.
Publicado: (2019)

Salvianolic acid B prevents epithelial-to-mesenchymal transition through the TGF-β1 signal transduction pathway in vivo and in vitro
por: Wang, Qing-Lan, et al.
Publicado: (2010)

microRNA-141 inhibits TGF-β1-induced epithelial-to-mesenchymal transition through inhibition of the TGF-β1/SMAD2 signalling pathway in endometriosis
por: Wang, Sixue, et al.
Publicado: (2020)

A Crosstalk between the Smad and JNK Signaling in the TGF-β-Induced Epithelial-Mesenchymal Transition in Rat Peritoneal Mesothelial Cells
por: Liu, Qinghua, et al.
Publicado: (2012)

MicroRNA-182 targets SMAD7 to potentiate TGFβ-induced epithelial-mesenchymal transition and metastasis of cancer cells
por: Yu, Jingyi, et al.
Publicado: (2016)

HMGA2 facilitates epithelial-mesenchymal transition in renal cell carcinoma by regulating the TGF-β/Smad2 signaling pathway
por: Kou, Bo, et al.
Publicado: (2018)

TGF-β uses a novel mode of receptor activation to phosphorylate SMAD1/5 and induce epithelial-to-mesenchymal transition
por: Ramachandran, Anassuya, et al.
Publicado: (2018)

Sphingomyelin synthase 1 regulates the epithelial-to-mesenchymal transition mediated by the TGF-β/Smad pathway in MDA-MB-231 cells
por: Liu, Shuang, et al.
Publicado: (2019)

DcR3 induces epithelial-mesenchymal transition through activation of the TGF-β3/SMAD signaling pathway in CRC
por: Liu, Yan-Ping, et al.
Publicado: (2016)

Bleomycin (BLM) Induces Epithelial-to-Mesenchymal Transition in Cultured A549 Cells via the TGF-β/Smad Signaling Pathway
por: Chen, Kui-Jun, et al.
Publicado: (2016)

Polydatin ameliorates pulmonary fibrosis by suppressing inflammation and the epithelial mesenchymal transition via inhibiting the TGF-β/Smad signaling pathway
por: Qiu, Yue, et al.
Publicado: (2019)

KRT7 promotes epithelial-mesenchymal transition in ovarian cancer via the TGF-β/Smad2/3 signaling pathway
por: An, Qiang, et al.
Publicado: (2021)

Sildenafil Inhibits the Growth and Epithelial-to-mesenchymal Transition of Cervical Cancer via the TGF-β1/Smad2/3 Pathway
por: Liu, Ping, et al.
Publicado: (2023)

β-catenin activates TGF-β-induced epithelial–mesenchymal transition in adenomyosis
por: Yoo, Jung-Yoon, et al.
Publicado: (2020)

[Corrigendum] MicroRNA-133b targets TGFβ receptor I to inhibit TGF-β-induced epithelial-to-mesenchymal transition and metastasis by suppressing the TGF-β/SMAD pathway in breast cancer
por: Wang, Shengjie, et al.
Publicado: (2023)

IL-27 inhibits the TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells
por: Dong, Zhaoxing, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_aq9p7qrvkc2pft6iijtkklc0d8