Synthesis and post-functionalization of alternate-linked-meta-para-[2(n).1(n)]thiacyclophanes

In recent decades, considerable research attention has been devoted to new synthetic procedures for thiacyclophanes. Thiacyclophanes are widely used as host molecules for the molecular recognition of organic compounds as well as metals. Herein, we report the selective and high-yielding synthesis of...

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Autores principales: De Leger, Wout, Adriaensen, Koen, Robeyns, Koen, Van Meervelt, Luc, Thomas, Joice, Meijers, Björn, Smet, Mario, Dehaen, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2018
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122333/
https://www.ncbi.nlm.nih.gov/pubmed/30202471
http://dx.doi.org/10.3762/bjoc.14.192
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author De Leger, Wout
Adriaensen, Koen
Robeyns, Koen
Van Meervelt, Luc
Thomas, Joice
Meijers, Björn
Smet, Mario
Dehaen, Wim
author_facet De Leger, Wout
Adriaensen, Koen
Robeyns, Koen
Van Meervelt, Luc
Thomas, Joice
Meijers, Björn
Smet, Mario
Dehaen, Wim
author_sort De Leger, Wout
collection PubMed
description In recent decades, considerable research attention has been devoted to new synthetic procedures for thiacyclophanes. Thiacyclophanes are widely used as host molecules for the molecular recognition of organic compounds as well as metals. Herein, we report the selective and high-yielding synthesis of novel alternate-linked-meta-para-thiacyclophanes. These novel thiacyclophanes are selectively synthesized in high-yielding procedures. Furthermore, post-functionalization of the phenolic moieties was successfully performed. The 3D structure of the alternate-linked-meta-para-[2(2).1(2)]thiacyclophane was further elucidated via X-ray crystallographic analysis.
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spelling pubmed-61223332018-09-10 Synthesis and post-functionalization of alternate-linked-meta-para-[2(n).1(n)]thiacyclophanes De Leger, Wout Adriaensen, Koen Robeyns, Koen Van Meervelt, Luc Thomas, Joice Meijers, Björn Smet, Mario Dehaen, Wim Beilstein J Org Chem Full Research Paper In recent decades, considerable research attention has been devoted to new synthetic procedures for thiacyclophanes. Thiacyclophanes are widely used as host molecules for the molecular recognition of organic compounds as well as metals. Herein, we report the selective and high-yielding synthesis of novel alternate-linked-meta-para-thiacyclophanes. These novel thiacyclophanes are selectively synthesized in high-yielding procedures. Furthermore, post-functionalization of the phenolic moieties was successfully performed. The 3D structure of the alternate-linked-meta-para-[2(2).1(2)]thiacyclophane was further elucidated via X-ray crystallographic analysis. Beilstein-Institut 2018-08-22 /pmc/articles/PMC6122333/ /pubmed/30202471 http://dx.doi.org/10.3762/bjoc.14.192 Text en Copyright © 2018, De Leger et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0). Please note that the reuse, redistribution and reproduction in particular requires that the authors and source are credited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
De Leger, Wout
Adriaensen, Koen
Robeyns, Koen
Van Meervelt, Luc
Thomas, Joice
Meijers, Björn
Smet, Mario
Dehaen, Wim
Synthesis and post-functionalization of alternate-linked-meta-para-[2(n).1(n)]thiacyclophanes
title Synthesis and post-functionalization of alternate-linked-meta-para-[2(n).1(n)]thiacyclophanes
title_full Synthesis and post-functionalization of alternate-linked-meta-para-[2(n).1(n)]thiacyclophanes
title_fullStr Synthesis and post-functionalization of alternate-linked-meta-para-[2(n).1(n)]thiacyclophanes
title_full_unstemmed Synthesis and post-functionalization of alternate-linked-meta-para-[2(n).1(n)]thiacyclophanes
title_short Synthesis and post-functionalization of alternate-linked-meta-para-[2(n).1(n)]thiacyclophanes
title_sort synthesis and post-functionalization of alternate-linked-meta-para-[2(n).1(n)]thiacyclophanes
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122333/
https://www.ncbi.nlm.nih.gov/pubmed/30202471
http://dx.doi.org/10.3762/bjoc.14.192
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