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Online structure-based screening of purchasable approved drugs and natural compounds: retrospective examples of drug repositioning on cancer targets
Drug discovery is a long and difficult process that benefits from the integration of virtual screening methods in experimental screening campaigns such as to generate testable hypotheses, accelerate and/or reduce the cost of drug development. Current drug attrition rate is still a major issue in all...
Autores principales: | Lagarde, Nathalie, Rey, Julien, Gyulkhandanyan, Aram, Tufféry, Pierre, Miteva, Maria A., Villoutreix, Bruno O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122352/ https://www.ncbi.nlm.nih.gov/pubmed/30190791 http://dx.doi.org/10.18632/oncotarget.25966 |
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