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Treatment of bilateral ovarian dysgerminoma with 11-year follow-up: A case report

INTRODUCTION: Malignant ovarian germ cell tumors (MOGCTs) are rare malignancies with an incidence of about 0.5/100,000. They account for less than 5% of all ovarian tumors, of which 32.8% are dysgerminomas, the female analogue of seminomas. These tumors occur in all age groups, with peak incidence b...

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Detalles Bibliográficos
Autores principales: Zogbi, Luciano, Gonçalves, Carla Vitola, Tejada, Victor Felipe, Martins, Daiane, Karam, Fabine, Machado dos Santos, Sílvia, Caldeira, Roberta Raseira, Senhorin, Gisele Zanetti, Lauz, Susi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122391/
https://www.ncbi.nlm.nih.gov/pubmed/30186597
http://dx.doi.org/10.1016/j.amsu.2018.08.009
Descripción
Sumario:INTRODUCTION: Malignant ovarian germ cell tumors (MOGCTs) are rare malignancies with an incidence of about 0.5/100,000. They account for less than 5% of all ovarian tumors, of which 32.8% are dysgerminomas, the female analogue of seminomas. These tumors occur in all age groups, with peak incidence below the age of 20 years in women. AIM: To describe the case of a bilateral ovarian dysgerminoma treatment with 11-year follow-up. METHODS: Case report with details regarding clinical history, surgical treatment, chemotherapy and follow up. We include a brief literature review. RESULTS: The patient underwent radical surgery for an advanced dysgerminoma, 20 cm in length, that compromised the contralateral ovary and sigmoid. Neoplastic cells were found in ascitic fluid. Subsequently, she underwent adjuvant chemotherapy according to a standard protocol. She has survived disease-free for more than 11 years. CONCLUSIONS: Dysgerminoma is a malignant neoplasm that, similar to other cancers, is easier to treat when diagnosed early. However, cures may be obtained even in advanced cases.