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Treatment of bilateral ovarian dysgerminoma with 11-year follow-up: A case report

INTRODUCTION: Malignant ovarian germ cell tumors (MOGCTs) are rare malignancies with an incidence of about 0.5/100,000. They account for less than 5% of all ovarian tumors, of which 32.8% are dysgerminomas, the female analogue of seminomas. These tumors occur in all age groups, with peak incidence b...

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Autores principales: Zogbi, Luciano, Gonçalves, Carla Vitola, Tejada, Victor Felipe, Martins, Daiane, Karam, Fabine, Machado dos Santos, Sílvia, Caldeira, Roberta Raseira, Senhorin, Gisele Zanetti, Lauz, Susi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122391/
https://www.ncbi.nlm.nih.gov/pubmed/30186597
http://dx.doi.org/10.1016/j.amsu.2018.08.009
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author Zogbi, Luciano
Gonçalves, Carla Vitola
Tejada, Victor Felipe
Martins, Daiane
Karam, Fabine
Machado dos Santos, Sílvia
Caldeira, Roberta Raseira
Senhorin, Gisele Zanetti
Lauz, Susi
author_facet Zogbi, Luciano
Gonçalves, Carla Vitola
Tejada, Victor Felipe
Martins, Daiane
Karam, Fabine
Machado dos Santos, Sílvia
Caldeira, Roberta Raseira
Senhorin, Gisele Zanetti
Lauz, Susi
author_sort Zogbi, Luciano
collection PubMed
description INTRODUCTION: Malignant ovarian germ cell tumors (MOGCTs) are rare malignancies with an incidence of about 0.5/100,000. They account for less than 5% of all ovarian tumors, of which 32.8% are dysgerminomas, the female analogue of seminomas. These tumors occur in all age groups, with peak incidence below the age of 20 years in women. AIM: To describe the case of a bilateral ovarian dysgerminoma treatment with 11-year follow-up. METHODS: Case report with details regarding clinical history, surgical treatment, chemotherapy and follow up. We include a brief literature review. RESULTS: The patient underwent radical surgery for an advanced dysgerminoma, 20 cm in length, that compromised the contralateral ovary and sigmoid. Neoplastic cells were found in ascitic fluid. Subsequently, she underwent adjuvant chemotherapy according to a standard protocol. She has survived disease-free for more than 11 years. CONCLUSIONS: Dysgerminoma is a malignant neoplasm that, similar to other cancers, is easier to treat when diagnosed early. However, cures may be obtained even in advanced cases.
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spelling pubmed-61223912018-09-05 Treatment of bilateral ovarian dysgerminoma with 11-year follow-up: A case report Zogbi, Luciano Gonçalves, Carla Vitola Tejada, Victor Felipe Martins, Daiane Karam, Fabine Machado dos Santos, Sílvia Caldeira, Roberta Raseira Senhorin, Gisele Zanetti Lauz, Susi Ann Med Surg (Lond) Case Report INTRODUCTION: Malignant ovarian germ cell tumors (MOGCTs) are rare malignancies with an incidence of about 0.5/100,000. They account for less than 5% of all ovarian tumors, of which 32.8% are dysgerminomas, the female analogue of seminomas. These tumors occur in all age groups, with peak incidence below the age of 20 years in women. AIM: To describe the case of a bilateral ovarian dysgerminoma treatment with 11-year follow-up. METHODS: Case report with details regarding clinical history, surgical treatment, chemotherapy and follow up. We include a brief literature review. RESULTS: The patient underwent radical surgery for an advanced dysgerminoma, 20 cm in length, that compromised the contralateral ovary and sigmoid. Neoplastic cells were found in ascitic fluid. Subsequently, she underwent adjuvant chemotherapy according to a standard protocol. She has survived disease-free for more than 11 years. CONCLUSIONS: Dysgerminoma is a malignant neoplasm that, similar to other cancers, is easier to treat when diagnosed early. However, cures may be obtained even in advanced cases. Elsevier 2018-08-21 /pmc/articles/PMC6122391/ /pubmed/30186597 http://dx.doi.org/10.1016/j.amsu.2018.08.009 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Zogbi, Luciano
Gonçalves, Carla Vitola
Tejada, Victor Felipe
Martins, Daiane
Karam, Fabine
Machado dos Santos, Sílvia
Caldeira, Roberta Raseira
Senhorin, Gisele Zanetti
Lauz, Susi
Treatment of bilateral ovarian dysgerminoma with 11-year follow-up: A case report
title Treatment of bilateral ovarian dysgerminoma with 11-year follow-up: A case report
title_full Treatment of bilateral ovarian dysgerminoma with 11-year follow-up: A case report
title_fullStr Treatment of bilateral ovarian dysgerminoma with 11-year follow-up: A case report
title_full_unstemmed Treatment of bilateral ovarian dysgerminoma with 11-year follow-up: A case report
title_short Treatment of bilateral ovarian dysgerminoma with 11-year follow-up: A case report
title_sort treatment of bilateral ovarian dysgerminoma with 11-year follow-up: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122391/
https://www.ncbi.nlm.nih.gov/pubmed/30186597
http://dx.doi.org/10.1016/j.amsu.2018.08.009
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