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Different sulfonylureas induce the apoptosis of proximal tubular epithelial cell differently via closing K(ATP) channel
BACKGROUND: Sulfonylureas (SUs) are widely prescribed for the treatment of type 2 diabetes (T2DM). Sulfonylurea receptors (SURs) are their main functional receptors. These receptors are also found in kidney, especially the tubular cells. However, the effects of SUs on renal proximal tubular epitheli...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122448/ https://www.ncbi.nlm.nih.gov/pubmed/30180807 http://dx.doi.org/10.1186/s10020-018-0042-5 |