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Different sulfonylureas induce the apoptosis of proximal tubular epithelial cell differently via closing K(ATP) channel

BACKGROUND: Sulfonylureas (SUs) are widely prescribed for the treatment of type 2 diabetes (T2DM). Sulfonylurea receptors (SURs) are their main functional receptors. These receptors are also found in kidney, especially the tubular cells. However, the effects of SUs on renal proximal tubular epitheli...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Zhou, Xiaojun, Shen, Xue, Xie, Tianyue, Xu, Chunmei, Zou, Zhiwei, Dong, Jianjun, Liao, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122448/
https://www.ncbi.nlm.nih.gov/pubmed/30180807
http://dx.doi.org/10.1186/s10020-018-0042-5