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PHF8 upregulation contributes to autophagic degradation of E-cadherin, epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma

BACKGROUND: Plant homeodomain finger protein 8 (PHF8) serves an activator of epithelial-mesenchymal transition (EMT) and is implicated in various tumors. However, little is known about PHF8 roles in hepatocellular carcinoma (HCC) and regulating E-cadherin expression. METHODS: PHF8 expression pattern...

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Detalles Bibliográficos
Autores principales:	Zhou, Wuhua, Gong, Li, Wu, Qinchuan, Xing, Chunyang, Wei, Bajin, Chen, Tianchi, Zhou, Yuan, Yin, Shengyong, Jiang, Bin, Xie, Haiyang, Zhou, Lin, Zheng, Shusen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122561/ https://www.ncbi.nlm.nih.gov/pubmed/30180906 http://dx.doi.org/10.1186/s13046-018-0890-4

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