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Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization

Two variant cohesin complexes containing SMC1, SMC3, RAD21 and either STAG/SA1 or SA2 are present in all cell types. We report here their genomic distribution and their specific contributions to genome organization in human cells. While both variants are found at CTCF sites, a fraction of cohesin-SA...

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Detalles Bibliográficos
Autores principales: Kojic, Aleksandar, Cuadrado, Ana, De Koninck, Magali, Giménez-Llorente, Daniel, Rodríguez-Corsino, Miriam, Gómez-López, Gonzalo, Le Dily, François, Marti-Renom, Marc A., Losada, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122591/
https://www.ncbi.nlm.nih.gov/pubmed/29867216
http://dx.doi.org/10.1038/s41594-018-0070-4

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