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Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization
Two variant cohesin complexes containing SMC1, SMC3, RAD21 and either STAG/SA1 or SA2 are present in all cell types. We report here their genomic distribution and their specific contributions to genome organization in human cells. While both variants are found at CTCF sites, a fraction of cohesin-SA...
Autores principales: | Kojic, Aleksandar, Cuadrado, Ana, De Koninck, Magali, Giménez-Llorente, Daniel, Rodríguez-Corsino, Miriam, Gómez-López, Gonzalo, Le Dily, François, Marti-Renom, Marc A., Losada, Ana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122591/ https://www.ncbi.nlm.nih.gov/pubmed/29867216 http://dx.doi.org/10.1038/s41594-018-0070-4 |
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